منابع مشابه
Pharmacological treatment of Parkinson disease: a review.
IMPORTANCE Parkinson disease is the second most common neurodegenerative disease worldwide. Although no available therapies alter the underlying neurodegenerative process, symptomatic therapies can improve patient quality of life. OBJECTIVE To provide an evidence-based review of the initial pharmacological management of the classic motor symptoms of Parkinson disease; describe management of m...
متن کاملSurgical treatment for Parkinson disease
Since the beginning of neurosurgery, operations have been carried out throughout the central nervous system to treat movement disorders. In the 1930's and 1940's, early neurosurgical procedures focused on pyramidal tract lesions for tremor resolutions, but tremor reduction came only at the expense of motor weakness. The era of basal ganglia surgery for Parkinson's disease (PD) began when Meyers...
متن کاملParkinson ’ s Disease and Its Treatment
Objectives: After reading this continuing education article, the pharmacist should be able to do the following: 1. Discuss the various etiologies of Parkinson’s disease. 2. Describe the major signs and symptoms associated with the disease. 3. Outline a rational therapeutic approach for the treatment of Parkinson’s disease. 4. Name the principal drugs and chemicals that may cause symptoms of the...
متن کاملPramipexole vs levodopa as initial treatment for Parkinson disease: A randomized controlled trial. Parkinson Study Group.
CONTEXT Pramipexole and levodopa both ameliorate the motor symptoms of early Parkinson disease (PD), but no controlled studies have compared long-term outcomes after initiating dopaminergic therapy with pramipexole vs levodopa. OBJECTIVE To compare the development of dopaminergic motor complications after initial treatment of early PD with pramipexole vs levodopa. DESIGN Multicenter, parall...
متن کاملCaffeine for treatment of Parkinson disease: a randomized controlled trial.
OBJECTIVE Epidemiologic studies consistently link caffeine, a nonselective adenosine antagonist, to lower risk of Parkinson disease (PD). However, the symptomatic effects of caffeine in PD have not been adequately evaluated. METHODS We conducted a 6-week randomized controlled trial of caffeine in PD to assess effects upon daytime somnolence, motor severity, and other nonmotor features. Patien...
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ژورنال
عنوان ژورنال: JAMA
سال: 2020
ISSN: 0098-7484
DOI: 10.1001/jama.2020.1224